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Increasing intracellular Zn concentration via zinc ionophores can efficiently impair intracellular replication of a variety of RNA viruses, including poliovirus, influenza virus and COVID-19-causing SARS-CoV-2 coronavirus, as demonstrated with such zinc ionophores as pyrrolidine.

Zinc ionophores can increase importation of zinc into cells.

It does this by blocking RNA POLYMERASE, which is necessary for replication of.

Zinc in combination with a zinc ionophore (which helps zinc enter human cells) can inhibit viral replication in human cells. It is also available as a dietary supplement. ZINC is an essential mineral present in many foods.

ZINC, ionophores, supplements and COVID-19.